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Ultracet is used to treat moderate to severe pain.

Ultracet contains a combination of tramadol and acetaminophen.

Tramadol is a narcotic-like pain reliever.

Acetaminophen is a less potent pain reliever that increases the effects of tramadol.


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Ultracet has been approved by the FDA for the short-term (five days or less) management of acute pain. This medication is a centrally acting analgesic that controls pain through different mechanisms of action than non-steroidal anti-inflammatory drugs (NSAIDs), the most commonly used pain medications.

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As a result, Ultracet is not associated with the side effects that can result from NSAID use, such as gastrointestinal ulcers or bleeding. Ultracet combines Ultram (tramadol HCl), a leading prescription pain reliever, with the common non-prescription pain treatment, acetaminophen. Clinical trials have shown that the combination is more effective than either drug alone, providing longer duration than acetaminophen and a faster onset of action than tramadol.

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